General Description:

Jiachun Diagnostics Streptavidin Magnetic Microspheres are the gold standard for separation and processing of biotinylated nucleic acids, antibodies or other biotinylated ligands and targets. The extremely high binding affinity (Kd=10-15) of the streptavidin-biotin interaction has been used in a wide range of applications.

Benefits and Features

● This product uses superparamagnetic microspheres with uniform particle size and regular morphology
● Convenient and fast capture of target molecules and magnetic separation
● Direct and fast separation of any biotinylated molecule
● Flexible protocol, gentle and efficient liquid phase reaction kinetics
● Very low nonspecific binding of nucleotides and nucleic acids
● Very low nonspecific binding to small negatively charged proteins
● Small and uniform particle size ensures large surface area per mg of microspheres and high capacity for corresponding target molecules
● Low precipitation rate but high iron content ensures fast magnetic separation
● Biomagnetic protocol can be easily adjusted for automated platforms
● High batch-to-batch reproducibility ensures consistent results in your application

About Streptavidin Magnetic Microspheres

These superparamagnetic microspheres are approximately 1 μm, a monolayer of recombinant streptavidin is covalently coupled to the surface to ensure that the vast majority of biotin binding sites can bind not only free biotin but also biotinylated ligands/targets, and ensure consistency and reproducibility of results. Its specific and defined surface can achieve efficient capture, separation and downstream processing. Streptavidin magnetic microspheres have a large surface area, high capacity, and superparamagnetism. They can be tailored for automation solutions that require high throughput. The products have high standards in reproducibility (within and between batches) and automation operations, making your results reliable.

Application

Streptavidin-coupled immunomagnetic beads have been used and cited in a variety of applications. For example, direct/indirect separation and downstream processing of nucleic acids, proteins/peptides, and other target molecules. They are very suitable for sequence-specific DNA/RNA capture in nucleic acid-based diagnostics, especially samples with high chaotropic salt concentrations, immunodetection involving biotinylated small antigens, and applications incompatible with BSA (magnetic beads are not blocked with BSA). They can be easily and flexibly adjusted for automated processes.